Association Between Regular Use of Gastric Acid Suppressants and Subsequent Risk of Cholelithiasis: A Prospective Cohort Study of 0.47 Million Participants

Background: Gastric acid suppressants have a major impact on gut microbiome which in turn, may increase the risk of cholelithiasis, but epidemiological evidence remains unclear. We undertook this research to evaluate the association between regular use of proton pump inhibitors (PPIs) and H2-recepto...

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Bibliographic Details
Main Authors: Man Yang, Bin Xia, Yawen Lu, Qiangsheng He, Yanyan Lin, Ping Yue, Bing Bai, Chunlu Dong, Wenbo Meng, Jian Qi, Jinqiu Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.813587/full