The influence of folate pathway polymorphisms on high-dose methotrexaterelated toxicity and survival in children with non-Hodgkin malignant lymphoma

Background. We evaluated the influence of folate pathway polymorphisms on high-dose methotrexate (HD-MTX) related toxicity in paediatric patients with T-cell non-Hodgkin lymphoma (NHL). Patients and methods. In total, 30 NHL patients were genotyped for selected folate pathway polymorphisms.

Bibliographic Details
Main Authors: Erculj Nina, Kotnik Barbara Faganel, Debeljak Marusa, Jazbec Janez, Dolzan Vita
Format: Article
Language:English
Published: Sciendo 2014-09-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.2478/raon-2013-0076