The Interaction between Chondroitin Sulfate and Dermatan Sulfate Tetrasaccharides and Pleiotrophin

The Interaction between Chondroitin Sulfate and Dermatan Sulfate Tetrasaccharides and Pleiotrophin

Pleiotrophin (PTN) is a neurotrophic factor that participates in the development of the embryonic central nervous system (CNS) and neural stem cell regulation by means of an interaction with sulfated glycosaminoglycans (GAGs). Chondroitin sulfate (CS) is the natural ligand in the CNS. We have previo...

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Bibliographic Details
Main Authors: María Jose García-Jiménez, Myriam Torres-Rico, José L. de Paz, Pedro M. Nieto
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
carbohydrate–protein interaction
pleiotrophin
chondroitin sulfate
GAG synthesis
transient NMR methods
STD-NMR spectroscopy
Online Access:https://www.mdpi.com/1422-0067/23/6/3026

Internet

https://www.mdpi.com/1422-0067/23/6/3026

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