DNA methylation change of HIPK3 in Chinese rheumatoid arthritis and its effect on inflammation

DNA methylation change of HIPK3 in Chinese rheumatoid arthritis and its effect on inflammation

IntroductionHomeodomain-interacting protein kinase 3 (HIPK3) plays an important role in cell proliferation, apoptosis, and inflammation. Over-expression of HIPK3 in immune cells in rheumatoid arthritis (RA) has been reported. In this study, we investigated blood methylation levels and clinical chara...

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Bibliographic Details
Main Authors: Ping Jiang, Kai Wei, Lingxia Xu, Cen Chang, Runrun Zhang, Jianan Zhao, Yehua Jin, Linshuai Xu, Yiming Shi, Yi Qian, Songtao Sun, Shicheng Guo, Rongsheng Wang, Yingying Qin, Dongyi He
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
DNA methylation
rheumatoid arthritis
inflammation
HIPK3
methylation haplotypes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1087279/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1087279/full

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