Distribution and inter-regional relationship of amyloid-beta plaque deposition in a 5xFAD mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is the most common form of dementia. Although previous studies have selectively investigated the localization of amyloid-beta (Aβ) deposition in certain brain regions, a comprehensive characterization of the rostro-caudal distribution of Aβ plaques in the brain and their int...

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Main Authors: Ka Chun Tsui, Jaydeep Roy, Sze Chun Chau, Kah Hui Wong, Lei Shi, Chi Him Poon, Yingyi Wang, Tatyana Strekalova, Luca Aquili, Raymond Chuen-Chung Chang, Man-Lung Fung, You-qiang Song, Lee Wei Lim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.964336/full