Changes of lysosome by L-serine in rotenone-treated hippocampal neurons

Abstract Oxidative stress destroys cellular organelles and damages DNA, eventually leading to degenerative brain disorders. Persistent mitochondrial damage by oxidative stress eventually causes cells to inhibit the function of lysosomes. Rotenone used in this study inhibits complex 1 of the mitochon...

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Bibliographic Details
Main Authors: Sumin Shin, Su-Kyeong Hwang, Ji Young Mun
Format: Article
Language:English
Published: SpringerOpen 2023-01-01
Series:Applied Microscopy
Subjects:
Online Access:https://doi.org/10.1186/s42649-022-00084-z