Cladosporol A triggers apoptosis sensitivity by ROS-mediated autophagic flux in human breast cancer cells

Cladosporol A triggers apoptosis sensitivity by ROS-mediated autophagic flux in human breast cancer cells

Abstract Background Endophytes have proven to be an invaluable resource of chemically diverse secondary metabolites that act as excellent lead compounds for anticancer drug discovery. Here we report the promising cytotoxic effects of Cladosporol A (HPLC purified >98%) isolated from endophytic fun...

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Bibliographic Details
Main Authors: Mytre Koul, Ashok Kumar, Ramesh Deshidi, Vishal Sharma, Rachna D. Singh, Jasvinder Singh, Parduman Raj Sharma, Bhahwal Ali Shah, Sundeep Jaglan, Shashank Singh
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Cell Biology
Subjects:
Apoptosis
Breast cancer
Cladosporium cladosporioides
Cladosporol a
Endophytes
Reactive oxygen species
Online Access:http://link.springer.com/article/10.1186/s12860-017-0141-0

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http://link.springer.com/article/10.1186/s12860-017-0141-0

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