In silico study to predict promiscuous T cell and B cell-epitopes derived from the vaccine candidate antigens of Plasmodium vivax binding to MHC class-II alleles

In silico study to predict promiscuous T cell and B cell-epitopes derived from the vaccine candidate antigens of Plasmodium vivax binding to MHC class-II alleles

Malaria is one of the major causes of health and disability globally, even after tremendous efforts to eradicate it. Till date no highly effective vaccine is available for its control. The primary reason for the low efficacy of vaccines is extensive polymorphism in potential vaccine candidate antige...

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Bibliographic Details
Main Authors: Nazam Khan, Mona N bin-Mwena, Mashael W Alruways, Noor Motair M Allehyani, Maryam Owaid Alanzi, Shahzad, Amir Khan, Rakesh Sehgal, P K Tripathi, Umar Farooq
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Journal of Vector Borne Diseases
Subjects:
epitopes; malaria; hla; immunodiagnostic; promiscuous peptides; homology modelling; subunit vaccine; pppk-dhps; dhfr-ts
Online Access:http://www.jvbd.org/article.asp?issn=0972-9062;year=2022;volume=59;issue=2;spage=154;epage=162;aulast=Khan

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http://www.jvbd.org/article.asp?issn=0972-9062;year=2022;volume=59;issue=2;spage=154;epage=162;aulast=Khan

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