Long-Term Capsaicin Administration Ameliorates the Dysfunction and Astrogliosis of the Brain in Aged Mice with Missing Maxillary Molars

Long-Term Capsaicin Administration Ameliorates the Dysfunction and Astrogliosis of the Brain in Aged Mice with Missing Maxillary Molars

Tooth loss and decreased masticatory function reportedly affect cognitive function; tooth loss allegedly induces astrogliosis and aging of astrocytes in the hippocampus and hypothalamus, which is a response specific to the central nervous system owing to homeostasis in different brain regions. Capsa...

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Bibliographic Details
Main Authors: Masae Furukawa, Hirobumi Tada, Resmi Raju, Jingshu Wang, Haruna Yokoi, Yoriko Ikuyo, Mitsuyoshi Yamada, Yosuke Shikama, Kenji Matsushita
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Nutrients
Subjects:
capsaicin
GFAP
s100β
TRPV1
mastication
brain aging
Online Access:https://www.mdpi.com/2072-6643/15/11/2471

Internet

https://www.mdpi.com/2072-6643/15/11/2471

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