Initial Steps for the Development of a Phage-Mediated Gene Replacement Therapy Using CRISPR-Cas9 Technology

Initial Steps for the Development of a Phage-Mediated Gene Replacement Therapy Using CRISPR-Cas9 Technology

p53 gene (<i>TP53</i>) replacement therapy has shown promising results in cancer gene therapy. However, it has been hampered, mostly because of the gene delivery vector of choice. CRISPR-Cas9 technology (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein...

Full description

Bibliographic Details
Main Authors: Jordi Yang Zhou, Keittisak Suwan, Amin Hajitou
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Journal of Clinical Medicine
Subjects:
bacteriophage
gene therapy
CRISPR-Cas9
p53
lung cancer
tumour suppressor gene replacement therapy
Online Access:https://www.mdpi.com/2077-0383/9/5/1498

Internet

https://www.mdpi.com/2077-0383/9/5/1498

Similar Items