Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells

Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells

Chimeric antigen receptor technology offers a highly effective means for increasing the anti-tumor effects of autologous adoptive T-cell immunotherapy, and could be made widely available if adapted to the use of allogeneic T-cells. Although gene-editing technology can be used to remove the alloreact...

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Bibliographic Details
Main Authors: Román Galetto, Celine Lebuhotel, Laurent Poirot, Agnès Gouble, Maria L Toribio, Julianne Smith, Andrew Scharenberg
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050116300870

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http://www.sciencedirect.com/science/article/pii/S2329050116300870

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