Mitochondrial DNA copy number variation across three generations: a possible biomarker for assessing perinatal outcomes

Mitochondrial DNA copy number variation across three generations: a possible biomarker for assessing perinatal outcomes

Abstract Background Mitochondria have their own circular multi-copy genome (mtDNA), and abnormalities in the copy number are implicated in mitochondrial dysfunction, which contributes to a variety of aging-related pathologies. However, not much is known about the genetic correlation of mtDNA copy nu...

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Bibliographic Details
Main Authors: Hisanori Fukunaga, Atsuko Ikeda
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Human Genomics
Subjects:
Birth cohort
Cord blood
DNA copy number variation
Maternal exposure
Mitochondrial DNA
Online Access:https://doi.org/10.1186/s40246-023-00567-4

Internet

https://doi.org/10.1186/s40246-023-00567-4

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