Deep-sequencing protocols influence the results obtained in small-RNA sequencing.

Second-generation sequencing is a powerful method for identifying and quantifying small-RNA components of cells. However, little attention has been paid to the effects of the choice of sequencing platform and library preparation protocol on the results obtained. We present a thorough comparison of s...

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Bibliographic Details
Main Authors: Joern Toedling, Nicolas Servant, Constance Ciaudo, Laurent Farinelli, Olivier Voinnet, Edith Heard, Emmanuel Barillot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22384282/?tool=EBI