Structural Evolution of the Protein Kinase-Like Superfamily.

The protein kinase family is large and important, but it is only one family in a larger superfamily of homologous kinases that phosphorylate a variety of substrates and play important roles in all three superkingdoms of life. We used a carefully constructed structural alignment of selected kinases a...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-10-01
Series:PLoS Computational Biology
Online Access:http://dx.doi.org/10.1371/journal.pcbi.0010049