UCP2, a Member of the Mitochondrial Uncoupling Proteins: An Overview from Physiological to Pathological Roles

UCP2 is an uncoupling protein homolog to UCP1. Unlike UCP1, which participates in non-shivering thermogenesis by uncoupling oxidative phosphorylation (OXPHOS), UCP2 does not perform a canonical H<sup>+</sup> leak, consuming the protonmotive force (Δ<i>p</i>) through the inner...

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Bibliographic Details
Main Authors: Salvatore Nesci, Speranza Rubattu
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/12/6/1307