A direct contact pig influenza challenge model for assessing protective efficacy of monoclonal antibodies

Monoclonal antibodies (mAbs) can be used to complement immunization for the therapy of influenza virus infection. We have established the pig, a natural large animal host for influenza A, with many physiological, immunological, and anatomical similarities to humans, as an appropriate model for testi...

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Bibliographic Details
Main Authors: Adam McNee, Daryll Vanover, Pramila Rijal, Basudev Paudyal, Fabian Z. X. Lean, Ronan MacLoughlin, Alejandro Núñez, Alain Townsend, Philip J. Santangelo, Elma Tchilian
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1229051/full