Immunogenicity and Protective Efficacy of a Recombinant Pichinde Viral-Vectored Vaccine Expressing Influenza Virus Hemagglutinin Antigen in Pigs

Immunogenicity and Protective Efficacy of a Recombinant Pichinde Viral-Vectored Vaccine Expressing Influenza Virus Hemagglutinin Antigen in Pigs

Influenza A virus of swine (IAV-S) is an economically important swine pathogen. The IAV-S hemagglutinin (HA) surface protein is the main target for vaccine development. In this study, we evaluated the feasibility of using the recombinant tri-segmented Pichinde virus (rPICV) as a viral vector to deli...

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Bibliographic Details
Main Authors: Sushmita Kumari, Jayeshbhai Chaudhari, Qinfeng Huang, Phillip Gauger, Marcelo Nunes De Almeida, Yuying Liang, Hinh Ly, Hiep L. X. Vu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Vaccines
Subjects:
swine influenza
vaccine
hemagglutinin
pichinde virus
arenavirus
viral vector vaccine
Online Access:https://www.mdpi.com/2076-393X/10/9/1400

Internet

https://www.mdpi.com/2076-393X/10/9/1400

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