A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus.

A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus.

Systemic lupus erythematosus (SLE) is a chronic, remitting, and relapsing, inflammatory disease involving multiple organs, which exhibits abnormalities of both the innate and adaptive immune responses. A limited number of transcriptomic studies have characterized the gene pathways involved in SLE in...

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Bibliographic Details
Main Authors: Yupeng Li, Richard E Higgs, Robert W Hoffman, Ernst R Dow, Xiong Liu, Michelle Petri, Daniel J Wallace, Thomas Dörner, Brian J Eastwood, Bradley B Miller, Yushi Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225651

Internet

https://doi.org/10.1371/journal.pone.0225651

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