Associations of B‐Type Natriuretic Peptide and Its Coding Gene Promoter Methylation With Functional Outcome of Acute Ischemic Stroke: A Mediation Analysis

Associations of B‐Type Natriuretic Peptide and Its Coding Gene Promoter Methylation With Functional Outcome of Acute Ischemic Stroke: A Mediation Analysis

Background The prognostic role of B‐type natriuretic peptide (BNP) in stroke has been suggested, but limited studies have shown mixed results and unknown underlying mechanisms. DNA methylation, a molecular modification that alters gene expression, may represent a candidate mechanism for this purpose...

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Bibliographic Details
Main Authors: Aili Wang, Mingzhi Zhang, Yi Ding, Xingbo Mo, Chongke Zhong, Zhengbao Zhu, Daoxia Guo, Xiaowei Zheng, Tan Xu, Yan Liu, Yonghong Zhang, Hao Peng
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
B‐type natriuretic peptide
DNA methylation
functional outcome
ischemic stroke
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.017499

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.017499

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