Inhibiting PLA2G7 reverses the immunosuppressive function of intratumoral macrophages and augments immunotherapy response in hepatocellular carcinoma

Inhibiting PLA2G7 reverses the immunosuppressive function of intratumoral macrophages and augments immunotherapy response in hepatocellular carcinoma

Background Hepatocellular carcinoma (HCC) is an exceptionally immunosuppressive malignancy characterized by limited treatment options and a dismal prognosis. Macrophages constitute the primary and heterogeneous immune cell population within the HCC microenvironment. Our objective is to identify dist...

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Bibliographic Details
Main Authors: Feng Zhang, Zhiyong Liu, Ling Dong, Wenfeng Liu, Fansheng Meng, Qiuyu Jiang, Wenqing Tang, Xiahui Lin, Ruyi Xue, Si Zhang
Format: Article
Language:English
Published: BMJ Publishing Group 2024-01-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/1/e008094.full

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https://jitc.bmj.com/content/12/1/e008094.full

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