Yeast based small molecule screen for inhibitors of SARS-CoV.

Yeast based small molecule screen for inhibitors of SARS-CoV.

Severe acute respiratory coronavirus (SARS-CoV) emerged in 2002, resulting in roughly 8000 cases worldwide and 10% mortality. The animal reservoirs for SARS-CoV precursors still exist and the likelihood of future outbreaks in the human population is high. The SARS-CoV papain-like protease (PLP) is a...

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Bibliographic Details
Main Authors: Matthew Frieman, Dipanwita Basu, Krystal Matthews, Justin Taylor, Grant Jones, Raymond Pickles, Ralph Baric, Daniel A Engel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3229576?pdf=render

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http://europepmc.org/articles/PMC3229576?pdf=render

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