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OBJECTIVES/SPECIFIC AIMS: We previously developed a translationally relevant model of temporal lobe epilepsy (TLE) in which glutamine synthetase is irreversibility inhibited by methionine sulfoximine (MSO), resulting in spontaneous seizures and dentate hilar neuron loss. The objective of this study...

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Bibliographic Details
Main Authors: Shaun Evan Gruenbaum, Roni Dhaher, Amedeo Rapuano, Tore Eid
Format: Article
Language:English
Published: Cambridge University Press 2017-09-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S205986611700200X/type/journal_article