Isorhamnetin and anti-PD-L1 antibody dual-functional mesoporous silica nanoparticles improve tumor immune microenvironment and inhibit YY1-mediated tumor progression

Abstract Background The immune checkpoint inhibitor (ICI) anti-PD-L1 monoclonal antibody can inhibit the progress of hepatocellular carcinoma (HCC). Epithelial–mesenchymal transformation (EMT) can promote tumor migration and the formation of immune-suppression microenvironment, which affects the the...

Full description

Bibliographic Details
Main Authors: Huijuan Liu, Jingxia Han, Ying Lv, Zihan Zhao, Shaoting Zheng, Yu Sun, Tao Sun
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-023-01967-3