GSK3 inhibitor-BIO regulates proliferation of immortalized pancreatic mesenchymal stem cells (iPMSCs).

GSK3 inhibitor-BIO regulates proliferation of immortalized pancreatic mesenchymal stem cells (iPMSCs).

BACKGROUND: The small molecule 6-bromoindirubin-30-oxime (BIO), a glycogen synthase kinase 3 (GSK3) inhibitor, is a pharmacological agent known to maintain self-renewal in human and mouse embryonic stem cells (ESCs). However, the precise role of GSK3 in immortalized pancreatic mesenchymal stem cells...

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Bibliographic Details
Main Authors: Hui Cao, Yuankui Chu, Xiao Lv, Pubin Qiu, Chao Liu, Huiru Zhang, Dan Li, Sha Peng, Zhongying Dou, Jinlian Hua
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3285662?pdf=render

Internet

http://europepmc.org/articles/PMC3285662?pdf=render

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