Efficient acquisition of tens of thousands of short tandem repeats in single-cell whole-genome-amplified DNA

Efficient acquisition of tens of thousands of short tandem repeats in single-cell whole-genome-amplified DNA

Summary: Short tandem repeats (STRs) are highly abundant in the human genome, but existing approaches for accurate genotyping of STRs are limited. Here, we describe a protocol for duplex molecular inversion probes for high-throughput and cost-effective STR enrichment. We have successfully tested pan...

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Bibliographic Details
Main Authors: Liming Tao, Zipora Marx, Ofir Raz, Ehud Shapiro
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:STAR Protocols
Subjects:
Single Cell
Genomics
Sequencing
High Throughput Screening
Molecular Biology
Molecular/Chemical Probes
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721005347

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http://www.sciencedirect.com/science/article/pii/S2666166721005347

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