Matrine alleviates depressive-like behaviors via modulating microbiota–gut–brain axis in CUMS-induced mice

Matrine alleviates depressive-like behaviors via modulating microbiota–gut–brain axis in CUMS-induced mice

Abstract Background The realization of the “microbiota–gut–brain” axis plays a critical role in neuropsychiatric disorders, particularly depression, is advancing rapidly. Matrine is a natural bioactive compound, which has been found to possess potential antidepressant effect. However, the underlying...

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Bibliographic Details
Main Authors: Ming Zhang, Aoqiang Li, Qifang Yang, Jingyi Li, Lihua Zheng, Guannan Wang, Ying Sun, Yanxin Huang, Muqing Zhang, Zhenbo Song, Lei Liu
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Translational Medicine
Subjects:
Matrine
Depression
Gut microbiota
Metabolomics
Microbiota–gut–brain axis
Online Access:https://doi.org/10.1186/s12967-023-03993-z

Internet

https://doi.org/10.1186/s12967-023-03993-z

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