WWOX Controls Cell Survival, Immune Response and Disease Progression by pY33 to pS14 Transition to Alternate Signaling Partners

WWOX Controls Cell Survival, Immune Response and Disease Progression by pY33 to pS14 Transition to Alternate Signaling Partners

Tumor suppressor WWOX inhibits cancer growth and retards Alzheimer’s disease (AD) progression. Supporting evidence shows that the more strongly WWOX binds intracellular protein partners, the weaker is cancer cell growth in vivo. Whether this correlates with retardation of AD progression is unknown....

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Bibliographic Details
Main Authors: Tsung-Yun Liu, Ganesan Nagarajan, Ming-Fu Chiang, Shenq-Shyang Huang, Tzu-Chia Lin, Yu-An Chen, Chun-I Sze, Nan-Shan Chang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
tumor suppressor
p53
WWOX
TIAF1
binding proteins
cancer
Online Access:https://www.mdpi.com/2073-4409/11/14/2137

Internet

https://www.mdpi.com/2073-4409/11/14/2137

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