KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization

KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization

Dynamic microtubules play a critical role in cell structure and function. In nervous system, microtubules are the major route for cargo protein trafficking and they specially extend into and out of synapses to regulate synaptic development and plasticity. However, the detailed depolymerization mecha...

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Bibliographic Details
Main Authors: Rui Zheng, Yonglan Du, Xintai Wang, Tailin Liao, Zhe Zhang, Na Wang, Xiumao Li, Ying Shen, Lei Shi, Jianhong Luo, Jun Xia, Ziyi Wang, Junyu Xu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
microtubule depolymerization
spine invasion
cognition
long-term potentiation
KIF2C
Online Access:https://elifesciences.org/articles/72483

Internet

https://elifesciences.org/articles/72483

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