Customized bioreactor enables the production of 3D diaphragmatic constructs influencing matrix remodeling and fibroblast overgrowth

Customized bioreactor enables the production of 3D diaphragmatic constructs influencing matrix remodeling and fibroblast overgrowth

Abstract The production of skeletal muscle constructs useful for replacing large defects in vivo, such as in congenital diaphragmatic hernia (CDH), is still considered a challenge. The standard application of prosthetic material presents major limitations, such as hernia recurrences in a remarkable...

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Bibliografske podrobnosti
Main Authors: Edoardo Maghin, Eugenia Carraro, Daniele Boso, Arben Dedja, Mattia Giagante, Paola Caccin, Raluca Ana-Maria Barna, Silvia Bresolin, Alice Cani, Giulia Borile, Deborah Sandrin, Filippo Romanato, Francesca Cecchinato, Anna Urciuolo, Dorianna Sandonà, Paolo De Coppi, Piero G. Pavan, Martina Piccoli
Format: Article
Jezik:English
Izdano: Nature Portfolio 2022-04-01
Serija:npj Regenerative Medicine
Online dostop:https://doi.org/10.1038/s41536-022-00222-x

Internet

https://doi.org/10.1038/s41536-022-00222-x

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