Vitamin D3 eradicates Helicobacter pylori by inducing VDR-CAMP signaling

BackgroundVitamin D3 [VitD3, 1,25 (OH)2D3] is known to have immunomodulatory and anti-microbial properties; however, its activity against Helicobacter pylori is unclear. In this study, we established H. pylori infection models in wild-type and VitD3 receptor (VDR) knockdown mice and analyzed the eff...

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Bibliographic Details
Main Authors: Ye Zhang, Chunya Wang, Li Zhang, Jie Yu, Wenjie Yuan, Lei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1033201/full