Iron, Oxidative Stress, and Metabolic Dysfunction—Associated Steatotic Liver Disease

Excess free iron is a substrate for the formation of reactive oxygen species (ROS), thereby augmenting oxidative stress. Oxidative stress is a well-established cause of organ damage in the liver, the main site of iron storage. Ferroptosis, an iron-dependent mechanism of regulated cell death, has rec...

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Bibliographic Details
Main Authors: Sophie Gensluckner, Bernhard Wernly, Christian Datz, Elmar Aigner
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/13/2/208