Effects of Venlafaxine & Methadone Alone and in Combination with Spontaneous Morphine withdrawal Syndrome & Pain Sensation in Rats

Introduction: Methadone has been used as a drug to detoxify opioid tolerance. Naloxane precipitated morphine withdrawal behaviours were attenuated by venlafaxine as an antidepressant. On the contrary, after detoxifying the opioids, spontaneous withdrawal syndrome may occur with pain sensitivity. The...

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Bibliographic Details
Main Authors: Meisam Fadaei-kenarsary, Yaghoob Farbood, Seyed Mohammad Taghi Mansouri, Hadi Fathi Moghaddam
Format: Article
Language:English
Published: Iran University of Medical Sciences 2015-02-01
Series:Basic and Clinical Neuroscience
Subjects:
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-581-2&slc_lang=en&sid=1