Safety and efficacy of naldemedine in cancer patients with opioid-induced constipation: a pooled, subgroup analysis of two randomised controlled studies

Objective This post hoc, pooled, subgroup analysis of two randomised studies evaluated baseline characteristics that may influence the efficacy and safety of naldemedine in patients with opioid-induced constipation (OIC) and cancer.Methods Data for patients who received 0.2 mg naldemedine or placebo...

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Bibliographic Details
Main Authors: Iwao Osaka, Hiroto Ishiki, Takaaki Yokota, Yukio Tada, Hiroki Sato, Masaharu Okamoto, Eriko Satomi
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:ESMO Open
Online Access:https://esmoopen.bmj.com/content/4/4/e000527.full