Contact Pathway Function During Human Whole Blood Clotting on Procoagulant Surfaces

Microfluidic thrombosis assays allow the control of anticoagulation, hemodynamics, pharmacology, and procoagulant surfaces containing collagen ± tissue factor (TF). With corn trypsin inhibitor (CTI) ranging from low (1–4 μg/mL) to high levels (40–60 μg/mL), the function of Factor XIIa (FXIIa) can be...

Full description

Bibliographic Details
Main Authors: Shu Zhu, Bradley A. Herbig, Xinren Yu, Jason Chen, Scott L. Diamond
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2018.00209/full