Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers

Abstract Coronaviruses (CoV) are enveloped viruses and rely on their nucleocapsid N protein to incorporate the positive-stranded genomic RNA into the virions. CoV N proteins form oligomers but the mechanism and relevance underlying their multimerization remain to be fully understood. Using in vitro...

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Bibliographic Details
Main Authors: Yingying Cong, Franziska Kriegenburg, Cornelis A. M. de Haan, Fulvio Reggiori
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06062-w