Synthesis and Pharmacological Characterization of New Photocaged Agonists for Histamine H<sub>3</sub> and H<sub>4</sub> Receptors

The modulation of biological processes with light-sensitive chemical probes promises precise temporal and spatial control. Yet, the design and synthesis of suitable probes is a challenge for medicinal chemists. This article introduces a photocaging strategy designed to modulate the pharmacology of h...

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Bibliographic Details
Main Authors: Yang Zheng, Meichun Gao, Maikel Wijtmans, Henry F. Vischer, Rob Leurs
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/17/4/536