Tetrandrine alleviates oxaliplatin-induced mechanical allodynia via modulation of inflammation-related genes

Tetrandrine alleviates oxaliplatin-induced mechanical allodynia via modulation of inflammation-related genes

Oxaliplatin, a platinum-based chemotherapy drug, causes neuropathic pain, yet effective pharmacological treatments are lacking. Previously, we showed that tetrandrine (TET), with anti-inflammatory properties, reduces mechanical allodynia in nerve-injured mice. This study explores the effect of TET o...

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Bibliographic Details
Main Authors: Zhi-Ling Zhang, Zi-Yang Wu, Feng-Yu Liu, Hang-YuChen, Suo-Di Zhai
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
tetrandrine
oxaliplatin
mechanical allodynia
inflammation
RNA-Seq
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1333842/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2024.1333842/full

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