Advances in targeting the vacuolar proton-translocating ATPase (V-ATPase) for anti-fungal therapy

Advances in targeting the vacuolar proton-translocating ATPase (V-ATPase) for anti-fungal therapy

Vacuolar proton-translocating ATPase (V-ATPase) is a membrane-bound, multi-subunit enzyme that uses the energy of ATP hydrolysis to pump protons across membranes. V-ATPase activity is critical for pH homeostasis and organelle acidification as well as for generation of the membrane potential that dri...

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Detaylı Bibliyografya
Asıl Yazarlar: Summer R. Hayek, Samuel A. Lee, Karlett J. Parra
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2014-01-01
Seri Bilgileri:Frontiers in Pharmacology
Konular:
pH homeostasis
fungi V-ATPase
vacuolar proton pump
vacuolar acidification
C. albicans pathogenicity
anti-fungal target
Online Erişim:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00004/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00004/full

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