Lack of evidence for the pathogenic role of iron and HFE gene mutations in Brazilian patients with nonalcoholic steatohepatitis

Lack of evidence for the pathogenic role of iron and HFE gene mutations in Brazilian patients with nonalcoholic steatohepatitis

The hypothesis of the role of iron overload associated with HFE gene mutations in the pathogenesis of nonalcoholic steatohepatitis (NASH) has been raised in recent years. In the present study, biochemical and histopathological evidence of iron overload and HFE mutations was investigated in NASH pati...

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Bibliographic Details
Main Authors: M.M. Deguti, A.M. Sipahi, L.C.C. Gayotto, S.A. Palácios, P.L. Bittencourt, A.C. Goldberg, A.A. Laudanna, F.J. Carrilho, E.L.R. Cançado
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2003-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Fatty liver
Nonalcoholic steatohepatitis
Iron overload
HFE gene
Alanine aminotransferase
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000600009

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000600009

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