Enhancer remodeling activates NOTCH3 signaling to confer chemoresistance in advanced nasopharyngeal carcinoma

Enhancer remodeling activates NOTCH3 signaling to confer chemoresistance in advanced nasopharyngeal carcinoma

Abstract Acquired resistance to chemotherapy is one of the major causes of mortality in advanced nasopharyngeal carcinoma (NPC). However, effective strategies are limited and the underlying molecular mechanisms remain elusive. In this study, through transcriptomic profiling analysis of 23 tumor tiss...

Full description

Bibliographic Details
Main Authors: Lizhen Liu, Peng Deng, Sailan Liu, Jing Han Hong, Rong Xiao, Peiyong Guan, Yali Wang, Peili Wang, Jiuping Gao, Jinghong Chen, Yichen Sun, Jianfeng Chen, Hai-Qiang Mai, Jing Tan
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06028-z

Internet

https://doi.org/10.1038/s41419-023-06028-z

Similar Items