Targeting PP2A for cancer therapeutic modulation

Protein phosphatases play essential roles as negative regulators of kinases and signaling cascades involved in cytoskeletal organization. Protein phosphatase 2A (PP2A) is highly conserved and is the predominant serine/threonine phosphatase in the nervous system, constituting more than 70% of all neu...

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Bibliographic Details
Main Authors: Halle Ronk, Jared S. Rosenblum, Timothy Kung, Zhengping Zhuang
Format: Article
Language:English
Published: China Anti-Cancer Association 2022-10-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:https://www.cancerbiomed.org/content/19/10/1428