The effects of MYC on tumor immunity and immunotherapy

Abstract The oncogene MYC is dysregulated in a host of human cancers, and as an important point of convergence in multitudinous oncogenic signaling pathways, it plays a crucial role in tumor immune regulation in the tumor immune microenvironment (TIME). Specifically, MYC promotes the expression of i...

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Bibliographic Details
Main Authors: Jiajin Li, Tingyu Dong, Zhen Wu, Dacheng Zhu, Hao Gu
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01403-3