The Primary Cilium as a Biomarker in the Hypoxic Adaptation of Bone Marrow-Derived Mesenchymal Stromal Cells: A Role for the Secreted Frizzled-Related Proteins

A pivotal role in guiding mesenchymal stem cell (MSC) differentiation has recently been attributed to the primary cilium. This solitary, non-motile microtubule-based organelle emerging from the cell surface acts as a sensorial membrane structure reflecting developmental and adaptive processes associ...

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Bibliographic Details
Main Authors: Sébastien Proulx-Bonneau, Borhane Annabi
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Biomarker Insights
Online Access:https://doi.org/10.4137/BMI.S8247