Rhodanineacetic Acid Derivatives as Potential Drugs: Preparation, Hydrophobic Properties and Antifungal Activity of (5-Arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic Acids

Rhodanineacetic Acid Derivatives as Potential Drugs: Preparation, Hydrophobic Properties and Antifungal Activity of (5-Arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic Acids

Some [(5Z)-(5-arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)]acetic acids were prepared as potential antifungal compounds. The general synthetic approach to all synthesized compounds is presented. Lipophilicity of all the discussed rhodanine-3-acetic acid derivatives was analyzed using a revers...

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Bibliographic Details
Main Authors: Josef Jampilek, Jiri Kunes, Vejsova Marcela, Petra Hirsova, Jiri Dohnal, Veronika Opletalova, Jan Dolezel
Format: Article
Language:English
Published: MDPI AG 2009-10-01
Series:Molecules
Subjects:
[(5Z)-(5-arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)]acetic acids
synthesis
lipophilicity measurement
in vitro antifungal activity
Online Access:http://www.mdpi.com/1420-3049/14/10/4197/

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http://www.mdpi.com/1420-3049/14/10/4197/

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