Assessment of the targeted effect of Sijunzi decoction on the colorectal cancer microenvironment via the ESTIMATE algorithm.

<h4>Objective</h4>Sijunzi decoction (SJZD) was used to treat patients with colorectal cancer (CRC) as an adjuvant method. The aim of the study was to investigate the therapeutic targets and pathways of SJZD towards the tumor microenvironment of CRC via network pharmacology and the ESTIMA...

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Main Authors: Jiaxin Du, Quyuan Tao, Ying Liu, Zhanming Huang, He Jin, Wenjia Lin, Xinying Huang, Jingyan Zeng, Yongchang Zhao, Lingyu Liu, Qian Xu, Xue Han, Lixia Chen, Xin-Lin Chen, Yi Wen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0264720