ATP Binding Cassette Transporter Mediates Both Heme and Pesticide Detoxification in Tick Midgut Cells.

In ticks, the digestion of blood occurs intracellularly and proteolytic digestion of hemoglobin takes place in a dedicated type of lysosome, the digest vesicle, followed by transfer of the heme moiety of hemoglobin to a specialized organelle that accumulates large heme aggregates, called hemosomes....

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Main Authors: Flavio Alves Lara, Paula C Pohl, Ana Caroline Gandara, Jessica da Silva Ferreira, Maria Clara Nascimento-Silva, Gervásio Henrique Bechara, Marcos H F Sorgine, Igor C Almeida, Itabajara da Silva Vaz, Pedro L Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4530934?pdf=render