Bothrops jararaca peptide with anti-hypertensive action normalizes endothelium dysfunction involved in physiopathology of preeclampsia.

Preeclampsia, a pregnancy-specific syndrome characterized by hypertension, proteinuria and edema, is a major cause of fetal and maternal morbidity and mortality especially in developing countries. Bj-PRO-10c, a proline-rich peptide isolated from Bothrops jararaca venom, has been attributed with pote...

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Bibliographic Details
Main Authors: Gabriel Benedetti, Katia L P Morais, Juliano R Guerreiro, Eduardo Fontana de Oliveira, Mara Sandra Hoshida, Leandro Oliveira, Nelson Sass, Ivo Lebrun, Henning Ulrich, Claudiana Lameu, Antonio Carlos Martins de Camargo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3157462?pdf=render