Combined Treatment of Heteronemin and Tetrac Induces Antiproliferation in Oral Cancer Cells

Combined Treatment of Heteronemin and Tetrac Induces Antiproliferation in Oral Cancer Cells

Background: Heteronemin, a marine sesterterpenoid-type natural product, possesses an antiproliferative effect in cancer cells. In addition, heteronemin has been shown to inhibit <i>p53</i> expression. Our laboratory has demonstrated that the thyroid hormone deaminated analogue, tetrac, a...

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Main Authors: Chi-Hung Huang, Tung-Yung Huang, Wong-Jin Chang, Yi-shin Pan, Hung-Ru Chu, Zi-Lin Li, Sukanya Unson, Yu-Tang Chin, Chi-Yu Lin, Haw-Ming Huang, Chao-Nan Hsiung, Fabio Gionfra, Paolo De Vito, Jens Z. Pedersen, Sandra Incerpi, Yi-Ru Chen, Sheng-Yang Lee, Hung-Yun Lin, Paul J. Davis, Jacqueline Whang-Peng, Kuan Wang
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Marine Drugs
Subjects:
tetrac
heteronemin
oral cancer
antiproliferation
Online Access:https://www.mdpi.com/1660-3397/18/7/348

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https://www.mdpi.com/1660-3397/18/7/348

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