Biological nanopore approach for single‐molecule analysis of nucleobase modifications

Abstract Base modifications play an essential role in cellular function, and the abnormal expressions of base modifications are associated with numerous diseases. Unfortunately, existing detection methods have difficulty obtaining sequence information of various modified nucleobases at the single‐mo...

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Bibliographic Details
Main Authors: Pengrui Lv, Yongyi Yang, Shuang Li, Cherie S. Tan, Dong Ming
Format: Article
Language:English
Published: Wiley-VCH 2022-10-01
Series:Electrochemical Science Advances
Subjects:
Online Access:https://doi.org/10.1002/elsa.202100119