Clinical autism subscales have common genetic liabilities that are heritable, pleiotropic, and generalizable to the general population

Abstract The complexity of autism’s phenotypic spectra is well-known, yet most genetic research uses case-control status as the target trait. It is undetermined if autistic symptom domain severity underlying this heterogeneity is heritable and pleiotropic with other psychiatric and behavior traits i...

Full description

Bibliographic Details
Main Authors: Taylor R. Thomas, Tanner Koomar, Lucas G. Casten, Ashton J. Tener, Ethan Bahl, Jacob J. Michaelson
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01982-2